Mouse Hnrnpl activation kit by CRISPRa

SKU GA201940

Hnrnpl CRISPRa kit - CRISPR gene activation of mouse heterogeneous nuclear ribonucleoprotein L

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Hnrnpl
• Locus ID: 15388
• Components:

  GA201940G1, Hnrnpl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201940G2, Hnrnpl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201940G3, Hnrnpl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_177301
• UniProt ID: Q8R081
• Synonyms: C79783; D830027H13Rik; Hnrpl
• Summary: Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion (PubMed:22523384). Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.[UniProtKB/Swiss-Prot Function]