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Mouse Hmgcl activation kit by CRISPRa

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SKU
GA201919
Hmgcl CRISPRa kit - CRISPR gene activation of mouse 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
  $1,657.00
4 Weeks*

Other products for "Hmgcl"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Hmgcl
Locus ID 15356
Components

GA201919G1, Hmgcl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201919G2, Hmgcl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201919G3, Hmgcl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_008254, NM_001357529, NM_001357530
UniProt ID P38060
Synonyms AW476067; HL
Summary Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN507821 Hmgcl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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