Mouse Hhex activation kit by CRISPRa

SKU GA201895

Hhex CRISPRa kit - CRISPR gene activation of mouse hematopoietically expressed homeobox

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Hhex
• Locus ID: 15242
• Components:

  GA201895G1, Hhex gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201895G2, Hhex gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201895G3, Hhex gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_008245
• UniProt ID: P43120
• Synonyms: Hex; Hex1; Hhex-rs2; Prh; Prhx
• Summary: Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.[UniProtKB/Swiss-Prot Function]