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Mouse Gzmb activation kit by CRISPRa

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SKU
GA201793
Gzmb CRISPRa kit - CRISPR gene activation of mouse granzyme B
  $1,657.00
4 Weeks*

Other products for "Gzmb"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Gzmb
Locus ID 14939
Components

GA201793G1, Gzmb gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201793G2, Gzmb gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201793G3, Gzmb gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013542
UniProt ID P04187
Synonyms AI553453; CCP-1/C11; CCP1; Ctla-1; Ctla1; GZB
Summary This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. provided by RefSeq, Sep 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN507479 Gzmb - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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