Mouse Gnmt activation kit by CRISPRa

SKU GA201675

Gnmt CRISPRa kit - CRISPR gene activation of mouse glycine N-methyltransferase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Gnmt
• Locus ID: 14711
• Components:

  GA201675G1, Gnmt gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201675G2, Gnmt gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201675G3, Gnmt gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_010321, NM_001364890
• UniProt ID: Q9QXF8
• Summary: Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine (By similarity).[UniProtKB/Swiss-Prot Function]