Mouse Gnai2 activation kit by CRISPRa

SKU GA201649

Gnai2 CRISPRa kit - CRISPR gene activation of mouse guanine nucleotide binding protein (G protein), alpha inhibiting 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Gnai2
• Locus ID: 14678
• Components:

  GA201649G1, Gnai2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201649G2, Gnai2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201649G3, Gnai2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_008138
• UniProt ID: P08752
• Synonyms: C76432; Galphai2; Gia; Gnai-2
• Summary: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.[UniProtKB/Swiss-Prot Function]