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Mouse Gcgr activation kit by CRISPRa

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SKU
GA201567
Gcgr CRISPRa kit - CRISPR gene activation of mouse glucagon receptor
  $1,657.00
4 Weeks*

Other products for "Gcgr"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Gcgr
Locus ID 14527
Components

GA201567G1, Gcgr gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201567G2, Gcgr gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201567G3, Gcgr gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_008101
UniProt ID Q61606
Synonyms GR
Summary G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN506361 Gcgr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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