Mouse Fv1 activation kit by CRISPRa

SKU GA201489

Fv1 CRISPRa kit - CRISPR gene activation of mouse Friend virus susceptibility 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Fv1
• Locus ID: 14349
• Components:

  GA201489G1, Fv1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201489G2, Fv1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201489G3, Fv1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_010244
• UniProt ID: P70213
• Synonyms: Fv-1; Rv-1; Rv1
• Summary: Retroviral restriction factor that prevents infection by gammaretroviruses. Acts by interacting with the capsid protein ca after entry of the virus into the cell. This interaction presumably disrupt the capsid thereby inactivating the viral genome, making it unable to enter host nucleus and integrate into host genome.[UniProtKB/Swiss-Prot Function]