Mouse Fn1 activation kit by CRISPRa

SKU GA201457

Fn1 CRISPRa kit - CRISPR gene activation of mouse fibronectin 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Fn1
• Locus ID: 14268
• Components:

  GA201457G1, Fn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201457G2, Fn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201457G3, Fn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001276408, NM_001276409, NM_001276410, NM_001276411, NM_001276412, NM_001276413, NM_010233
• UniProt ID: P11276
• Synonyms: E330027I09; Fn; Fn-1
• Summary: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.[UniProtKB/Swiss-Prot Function]