Mouse Etv6 activation kit by CRISPRa

SKU GA201311

Etv6 CRISPRa kit - CRISPR gene activation of mouse ets variant 6

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Etv6
• Locus ID: 14011
• Components:

  GA201311G1, Etv6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201311G2, Etv6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201311G3, Etv6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001303102, NM_007961
• UniProt ID: P97360
• Synonyms: AW123102; AW557856; Tel
• Summary: This gene encodes a transcriptional repressor belonging to the ETS family of proteins. Knockout of this gene in mice results in embryonic lethality due to defective angiogenesis. In humans, this gene is often involved in chromosome rearrangements associated with specific cancers. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]