Mouse Eef1a1 activation kit by CRISPRa

SKU GA201185

Eef1a1 CRISPRa kit - CRISPR gene activation of mouse eukaryotic translation elongation factor 1 alpha 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Eef1a1
• Locus ID: 13627
• Components:

  GA201185G1, Eef1a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201185G2, Eef1a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201185G3, Eef1a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_010106
• UniProt ID: P10126
• Synonyms: MGC7551; MGC8115; MGC8209; MGC18758; MGC27859; MGC102592; MGC103271; MGC118397
• Summary: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.[UniProtKB/Swiss-Prot Function]