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Mouse Lefty1 activation kit by CRISPRa

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SKU
GA201162
Lefty1 CRISPRa kit - CRISPR gene activation of mouse left right determination factor 1
  $1,657.00
4 Weeks*

Other products for "Lefty1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Lefty1
Locus ID 13590
Components

GA201162G1, Lefty1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201162G2, Lefty1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201162G3, Lefty1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_010094
UniProt ID Q64280
Synonyms AI450052; Ebaf; Leftb; lefty; lefty-1; Stra3; Tgfb4
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. Mice lacking a functional copy of this gene exhibit embryonic lethality and defects in left-right patterning. provided by RefSeq, Aug 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN509216 Lefty1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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