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Mouse Dnmt3b activation kit by CRISPRa

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SKU
GA201110
Dnmt3b CRISPRa kit - CRISPR gene activation of mouse DNA methyltransferase 3B
  $1,657.00
4 Weeks*

Other products for "Dnmt3b"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Dnmt3b
Locus ID 13436
Components

GA201110G1, Dnmt3b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201110G2, Dnmt3b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201110G3, Dnmt3b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001003960, NM_001003961, NM_001003963, NM_001122997, NM_001271744, NM_001271745, NM_001271746, NM_001271747, NM_010068
UniProt ID O88509
Synonyms MmuIIIB
Summary This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. provided by RefSeq, Nov 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN504724 Dnmt3b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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