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Mouse Dmpk activation kit by CRISPRa

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SKU
GA201090
Dmpk CRISPRa kit - CRISPR gene activation of mouse dystrophia myotonica-protein kinase
  $1,657.00
4 Weeks*

Other products for "Dmpk"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Dmpk
Locus ID 13400
Components

GA201090G1, Dmpk gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201090G2, Dmpk gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201090G3, Dmpk gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001190490, NM_001190491, NM_032418, NR_126095
UniProt ID P54265
Synonyms DM; Dm15; DMK; MDPK; MT-PK
Summary The protein encoded by this gene is a serine/threonine protein kinase that contains coiled-coil and C-terminal membrane association domains. In the embryonic mouse, it is found in cardiac and skeletal myocytes where it appears to play a role in myogenesis. In adults, the transcript is localized to several tissues including brain, heart, and skeletal and smooth muscle, and a function in cytoskeletal remodeling has been described. Transcripts with expanded CUG repeats in the 3' untranslated region mediate alternative splicing of several genes and sequester RNA binding proteins and RNA transcripts that contain CAG repeats, resulting in myotonic dystrophy, an autosomal dominant neuromuscular disorder. Alternative splicing results in multiple protein coding and non-coding transcript variants. provided by RefSeq, Oct 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN504637 Dmpk - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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