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Mouse Dkk1 activation kit by CRISPRa

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SKU
GA201075
Dkk1 CRISPRa kit - CRISPR gene activation of mouse dickkopf WNT signaling pathway inhibitor 1
  $1,657.00
4 Weeks*

Other products for "Dkk1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Dkk1
Locus ID 13380
Components

GA201075G1, Dkk1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201075G2, Dkk1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201075G3, Dkk1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_010051
UniProt ID O54908
Synonyms mdkk-1
Summary Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:18524778). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (PubMed:26206087). Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning (PubMed:18505822).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN504599 Dkk1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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