Mouse Dcc activation kit by CRISPRa

SKU GA201028

Dcc CRISPRa kit - CRISPR gene activation of mouse deleted in colorectal carcinoma

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Dcc
• Locus ID: 13176
• Components:

  GA201028G1, Dcc gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA201028G2, Dcc gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA201028G3, Dcc gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_007831
• UniProt ID: P70211
• Synonyms: C030036D22Rik; Igdcc1
• Summary: Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.[UniProtKB/Swiss-Prot Function]