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Mouse Cux1 activation kit by CRISPRa

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SKU
GA200958
Cux1 CRISPRa kit - CRISPR gene activation of mouse cut-like homeobox 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

TA363689 CUX1 Antibody - middle region
100 ul
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Other products for "Cux1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cux1
Locus ID 13047
Components

GA200958G1, Cux1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200958G2, Cux1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200958G3, Cux1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001291233, NM_001291234, NM_001291238, NM_001291239, NM_001291240, NM_009986, NM_198602
UniProt ID P53564
Synonyms CDP; Cutl1; Cux; Cux-1
Summary Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III (PubMed:20510857). Also involved in the control of synaptogenesis (Probable). In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN504023 Cux1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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