Mouse Col1a1 activation kit by CRISPRa

SKU
GA200829
Col1a1 CRISPRa kit - CRISPR gene activation of mouse collagen, type I, alpha 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Col1a1
Locus ID 12842
Components

GA200829G1, Col1a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200829G2, Col1a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200829G3, Col1a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_007742
UniProt ID P11087
Synonyms Col1a-1; Cola-1; Cola1; Mov-13; Mov13
Summary This gene encodes the alpha-1 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-2 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice lacking the encoded protein die in utero caused by the rupture of a major blood vessel. Transgenic mice expressing significantly lower levels of this gene exhibit morphological and functional defects in mineralized and non-mineralized connective tissue and, progressive loss of hearing. provided by RefSeq, Nov 2015
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Other Versions
SKU Description Size Price
KN503624 Col1a1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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