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Mouse Col3a1 activation kit by CRISPRa

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SKU
GA200813
Col3a1 CRISPRa kit - CRISPR gene activation of mouse collagen, type III, alpha 1
  $1,657.00
4 Weeks*

Other products for "Col3a1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Col3a1
Locus ID 12825
Components

GA200813G1, Col3a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200813G2, Col3a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200813G3, Col3a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_009930
UniProt ID P08121
Synonyms AW550625; Col3a-1; Tsk-2; Tsk2
Summary This gene encodes the alpha-1 subunit of the fibril-forming type III collagen found in bone, cartilage, dentin, tendon, bone marrow stroma and other connective tissue. The encoded protein forms homotrimeric type III procollagen that undergoes proteolytic processing during fibril formation. A majority of mice lacking the encoded protein die within two days of birth but about 5% of the animals survive to adulthood. The surviving mice exhibit severe cortical malformation and experience significantly shorter lifespan. The mutant mouse named "tight skin 2" exhibiting systemic sclerosis phenotype was found to harbor a missense point mutation in this gene. A pseudogene of this gene has been defined on chromosome 8. provided by RefSeq, Nov 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN503635 Col3a1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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