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Mouse Col2a1 activation kit by CRISPRa

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SKU
GA200812
Col2a1 CRISPRa kit - CRISPR gene activation of mouse collagen, type II, alpha 1
  $1,657.00
4 Weeks*

Other products for "Col2a1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Col2a1
Locus ID 12824
Components

GA200812G1, Col2a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200812G2, Col2a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200812G3, Col2a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001113515, NM_031163
UniProt ID P28481
Synonyms Col2; Col2a; Col2a-1; Del1; Dmm; Lpk; Rgsc856
Summary This gene encodes the alpha-1 subunit of the fibril-forming type II collagen, the major component of cartilage and the vitreous humor of the eye. The encoded preproprotein forms homotrimeric, triple helical procollagen that undergoes proteolytic processing during fibirl formation. Mice harboring certain mutations in this gene exhibit severe chondrodysplasia characterized by short limbs and trunch, craniofacial deformities and cleft palate. A complete lack of the encoded protein in mice results in postnatal lethality. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. provided by RefSeq, Dec 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN503634 Col2a1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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