Mouse Tpp1 activation kit by CRISPRa

SKU
GA200760
Tpp1 CRISPRa kit - CRISPR gene activation of mouse tripeptidyl peptidase I
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tpp1
Locus ID 12751
Components

GA200760G1, Tpp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200760G2, Tpp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200760G3, Tpp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_009906
UniProt ID O89023
Synonyms Cln2; LPIC; TPP-1; TPP-I
Summary This gene encodes a lysosomal serine protease that cleaves N-terminal tripeptides from protein substrates. The encoded preproprotein undergoes autocatalytic processing to generate a mature enzyme. Mice lacking the encoded protein exhibit a progressive neurodegeneration and a greatly shortened lifespan. At the cellular level, mice lacking the encoded protein exhibit accumulation of autofluorescent lipopigments. Mutations in the human ortholog of this gene cause classical late-infantile neuronal ceroid lipofuscinosis. provided by RefSeq, Nov 2015
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Other Versions
SKU Description Size Price
KN518097 Tpp1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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