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Mouse Cldn5 activation kit by CRISPRa

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SKU
GA200755
Cldn5 CRISPRa kit - CRISPR gene activation of mouse claudin 5
  $1,657.00
4 Weeks*

Other products for "Cldn5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cldn5
Locus ID 12741
Components

GA200755G1, Cldn5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200755G2, Cldn5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200755G3, Cldn5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013805
UniProt ID O54942
Synonyms AI854493; MBEC1; Tmvcf
Summary This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a critical component of endothelial tight junctions that control pericellular permeability. The knockout mice lacking this gene died within 10 h of birth and the blood-brain barrier in these mice against small molecules was selectively affected. This gene is expressed strongly in endothelium of normal lung and plays a regulation role during acrolein-induced acute lung injury. provided by RefSeq, Aug 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN503420 Cldn5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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