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Mouse Cdkn2c activation kit by CRISPRa

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SKU
GA200681
Cdkn2c CRISPRa kit - CRISPR gene activation of mouse cyclin dependent kinase inhibitor 2C
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cdkn2c
Locus ID 12580
Components

GA200681G1, Cdkn2c gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200681G2, Cdkn2c gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200681G3, Cdkn2c gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001301368, NM_007671
UniProt ID Q60772
Synonyms C77269; INK4c; p18; p18-INK4c; p18-INK6; p18INK4c
Summary The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase (cdk) inhibitors, and contains five ankyrin repeats. This protein interacts with both Cdk4 and Cdk6 to inhibit their kinase activities, and prevent their interactions with D-type cyclins, thereby negatively regulating cell division. This gene is differentially expressed in a variety of tissues, and is cell cycle regulated. Deletion of this gene can lead to tumor growth. Maximal expression is observed at the G2/M phase. Alternative splicing and promoter usage results in multiple transript variants. provided by RefSeq, Aug 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN503065 Cdkn2c - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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