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Mouse Ctnna2 activation kit by CRISPRa

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SKU
GA200547
Ctnna2 CRISPRa kit - CRISPR gene activation of mouse catenin (cadherin associated protein), alpha 2
  $1,657.00
4 Weeks*

Other products for "Ctnna2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ctnna2
Locus ID 12386
Components

GA200547G1, Ctnna2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200547G2, Ctnna2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200547G3, Ctnna2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001109764, NM_009819, NM_145732, NM_001355193
UniProt ID Q61301
Synonyms AI481747; Catna; Catna2; cdf; chp
Summary May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (PubMed:12123610, PubMed:15034585). Required for proper regulation of cortical neuronal migration and neurite growth. It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization. It thereby suppresses excessive actin branching which would impair neurite growth and stability (By similarity). Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (PubMed:12089526).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN503964 Ctnna2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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