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Mouse Camk2a activation kit by CRISPRa

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SKU
GA200504
Camk2a CRISPRa kit - CRISPR gene activation of mouse calcium/calmodulin-dependent protein kinase II alpha
  $1,657.00
4 Weeks*

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Other products for "Camk2a"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Camk2a
Locus ID 12322
Components

GA200504G1, Camk2a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200504G2, Camk2a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200504G3, Camk2a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001286809, NM_009792, NM_177407
UniProt ID P11798
Synonyms CaMKII; mKIAA0968; R74975
Summary Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons (By similarity). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN502477 Camk2a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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