Mouse Aspm activation kit by CRISPRa

SKU
GA200500
Aspm CRISPRa kit - CRISPR gene activation of mouse abnormal spindle microtubule assembly
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Aspm
Locus ID 12316
Components

GA200500G1, Aspm gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200500G2, Aspm gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200500G3, Aspm gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_009791
UniProt ID Q8CJ27
Synonyms Calmbp1; D330028K02Rik; MCPH5; Sha1
Summary Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seem to depend on its association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed:28436967). May have a preferential role in regulating neurogenesis.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN501693 Aspm - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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