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Mouse Cacna1d activation kit by CRISPRa

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SKU
GA200478
Cacna1d CRISPRa kit - CRISPR gene activation of mouse calcium channel, voltage-dependent, L type, alpha 1D subunit
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cacna1d
Locus ID 12289
Components

GA200478G1, Cacna1d gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200478G2, Cacna1d gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200478G3, Cacna1d gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001083616, NM_001302637, NM_028981
UniProt ID Q99246
Synonyms 8430418G19Rik; C79217; Cach3; Cacn4; Cacnl1a2; Cav1.3; Cchl1a; Cchl1a2; D-LTCC
Summary This gene encodes a pore-forming subunit of the L-type, voltage-activated calcium channel family. These channels have been found to play a role in heart and smooth muscle contraction and in the transmission of auditory information. Homozygous knockout mice for this gene exhibit deafness and heart defects. These channels have also been linked to mitochondrial oxidative stress in a mouse model of Parkinson's disease. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Nov 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN502416 Cacna1d - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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