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Mouse Cacna1b activation kit by CRISPRa

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SKU
GA200476
Cacna1b CRISPRa kit - CRISPR gene activation of mouse calcium channel, voltage-dependent, N type, alpha 1B subunit
  $1,657.00
4 Weeks*

Other products for "Cacna1b"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cacna1b
Locus ID 12287
Components

GA200476G1, Cacna1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200476G2, Cacna1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200476G3, Cacna1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001042528, NM_007579
UniProt ID O55017
Synonyms alpha(1B); AW050276; AW060892; AW822256; BIII; Cav2.2; Cchn1a
Summary Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by omega-conotoxin-GVIA (AC P01522) (By similarity). They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN502414 Cacna1b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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