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Mouse C2 activation kit by CRISPRa

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SKU
GA200463
C2 CRISPRa kit - CRISPR gene activation of mouse complement component 2 (within H-2S)
  $1,657.00
4 Weeks*

Other products for "C2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol C2
Locus ID 12263
Components

GA200463G1, C2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200463G2, C2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200463G3, C2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013484
UniProt ID P21180
Summary This gene encodes component C2 of the classical pathway of the complement system. The encoded protein undergoes proteolytic processing mediated by component C1 resulting in C2a and C2b fragments. C2a fragment, in turn, selectively cleaves components C3 and C5 of the complement system. Mice lacking the encoded protein are found to be more susceptible to bacterial infections. Mutations in the human homolog of this gene are associated with disorders such as systemic lupus erythematosus, Henoch-Schonlein purpura, or polymyositis. provided by RefSeq, Mar 2015
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Other Versions
SKU Description Size Price
KN502363 C2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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