Mouse Btn1a1 activation kit by CRISPRa

SKU GA200451

Btn1a1 CRISPRa kit - CRISPR gene activation of mouse butyrophilin, subfamily 1, member A1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Btn1a1
• Locus ID: 12231
• Components:

  GA200451G1, Btn1a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200451G2, Btn1a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200451G3, Btn1a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_013483
• UniProt ID: Q62556
• Synonyms: Btn
• Summary: May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity). Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.[UniProtKB/Swiss-Prot Function]