Mouse Bach1 activation kit by CRISPRa

SKU GA200362

Bach1 CRISPRa kit - CRISPR gene activation of mouse BTB and CNC homology 1, basic leucine zipper transcription factor 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Bach1
• Locus ID: 12013
• Components:

  GA200362G1, Bach1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200362G2, Bach1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200362G3, Bach1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_007520
• UniProt ID: P97302
• Synonyms: 6230421P05Rik; AI323795
• Summary: Transcriptional regulator that acts as repressor or activator, depending on the context (PubMed:8887638, PubMed:19170764). Binds to NF-E2 DNA binding sites (PubMed:8887638, PubMed:19170764). Play important roles in coordinating transcription activation and repression by MAFK (PubMed:8887638). Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (By similarity).[UniProtKB/Swiss-Prot Function]