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Mouse Apoc1 activation kit by CRISPRa

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SKU
GA200241
Apoc1 CRISPRa kit - CRISPR gene activation of mouse apolipoprotein C-I
  $1,657.00
4 Weeks*

Other products for "Apoc1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Apoc1
Locus ID 11812
Components

GA200241G1, Apoc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200241G2, Apoc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200241G3, Apoc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001110009, NM_007469
UniProt ID P34928
Synonyms apo-CI; Apo-CIB; apoC-I; ApoC-IB
Summary This gene encodes a precursor plasma protein that is cleaved to yield a signal peptide and two alternatively processed mature peptides. The encoded protein, which is a component of chylomicrons, very low density lipoproteins and high density lipoproteins, transports lipids from the intestines to other locations in the body. This protein binds to free fatty acids preventing their uptake by cells. This protein is a cofactor for lecithin cholesterol acyltransferase, an enzyme that catalyzes the conversion of free cholesterol to cholesteryl esters. The encoded protein inhibits the activity of the cholesteryl ester transfer protein which promotes the exchange of neutral lipids between lipoproteins. In humans this gene is associated with risk of coronary artery disease and age-associated memory impairment. Mice lacking this gene demonstrate impaired memory. This gene is clustered with three other apolipoprotein genes on chromosome 7. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN501416 Apoc1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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