Mouse Amelx activation kit by CRISPRa

SKU GA200178

Amelx CRISPRa kit - CRISPR gene activation of mouse amelogenin, X-linked

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Amelx
• Locus ID: 11704
• Components:

  GA200178G1, Amelx gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA200178G2, Amelx gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA200178G3, Amelx gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001081978, NM_001290371, NM_009666
• UniProt ID: P63277
• Synonyms: ALGN; Amel; Amg; AMGL; AMGX; LRAP; Rgsc888
• Summary: Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.[UniProtKB/Swiss-Prot Function]