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Mouse Angpt4 activation kit by CRISPRa

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SKU
GA200121
Angpt4 CRISPRa kit - CRISPR gene activation of mouse angiopoietin 4
  $1,657.00
4 Weeks*

Other products for "Angpt4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Angpt4
Locus ID 11602
Components

GA200121G1, Angpt4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200121G2, Angpt4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200121G3, Angpt4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_009641
UniProt ID Q9WVH6
Synonyms Agpt4; ANG-3; ANG-4; Ang3
Summary This gene is a member of the angiopoietin family of secreted growth factors comprising Angiopoietins-1, -2, and -3, all of which bind the TEK Receptor Tyrosine Kinase. Angiopoietin/TEK Receptor Tyrosine Kinase signaling is involved in survival and migration of endothelial cells and regulates vascular remodeling and maintenance of vascular integrity. Angiopoietin/TEK Receptor Tyrosine Kinase signaling is also required for lymphangiogenesis. Family members bind TEK Receptor Tyrosine Kinase as multimeric clusters but their oligomerization properties differ from one another and this is thought to provide a mechanistic basis for their distinct physiologic roles. provided by RefSeq, Jul 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN501238 Angpt4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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