Human SFTPA2 activation kit by CRISPRa

SKU GA118992

SFTPA2 CRISPRa kit - CRISPR gene activation of human surfactant protein A2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SFTPA2
• Locus ID: 729238
• Components:

  GA118992G1, SFTPA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118992G2, SFTPA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118992G3, SFTPA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001098668, NM_001320813, NM_001320814
• UniProt ID: Q8IWL1
• Synonyms: COLEC5; PSAP; PSP-A; PSPA; SFTP1; SFTPA2B; SP-2A; SP-A; SPA2; SPAII
• Summary: This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009]