Human INS-IGF2 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | INS-IGF2 |
| Locus ID | 723961 |
| Components |
GA118882G1, INS-IGF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA118882G2, INS-IGF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA118882G3, INS-IGF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001042376, NM_001042377, NR_003512 |
| UniProt ID | F8WCM5 |
| Synonyms | INSIGF |
| Summary | This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. provided by RefSeq, Jul 2008 |
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