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Human CKMT1A activation kit by CRISPRa

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SKU
GA118617
CKMT1A CRISPRa kit - CRISPR gene activation of human creatine kinase, mitochondrial 1A
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC201239 CKMT1A (Myc-DDK-tagged)-Human creatine kinase, mitochondrial 1A (CKMT1A), nuclear gene encoding mitochondrial protein
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Other products for "CKMT1A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CKMT1A
Locus ID 548596
Components

GA118617G1, CKMT1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118617G2, CKMT1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118617G3, CKMT1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001015001, NM_001321926, NM_001321927, NM_001321928, NM_001321929, NR_135856
UniProt ID P12532
Synonyms CKMT1
Summary Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN401239 CKMT1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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