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Human TRIM72 activation kit by CRISPRa

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SKU
GA118577
TRIM72 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 72
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA385468 MG53 Rabbit polyclonal Antibody
100 ul
$380.00
RC218023 TRIM72 (Myc-DDK-tagged)-Human tripartite motif containing 72 (TRIM72)
10 ug
$457.00

Other products for "TRIM72"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRIM72
Locus ID 493829
Components

GA118577G1, TRIM72 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118577G2, TRIM72 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118577G3, TRIM72 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001008274
UniProt ID Q6ZMU5
Synonyms MG53
Summary Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN418023 TRIM72 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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