Human MARCHF11 activation kit by CRISPRa

SKU
GA118489
MARCH11 CRISPRa kit - CRISPR gene activation of human membrane associated ring-CH-type finger 11
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MARCHF11
Locus ID 441061
Components

GA118489G1, MARCHF11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118489G2, MARCHF11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118489G3, MARCHF11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001102562
UniProt ID A6NNE9
Synonyms MARCH-XI
Summary MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 PubMed 17604280).supplied by OMIM, Apr 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN419988 MARCH11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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