Human LC3C (MAP1LC3C) activation kit by CRISPRa

SKU GA118477

MAP1LC3C CRISPRa kit - CRISPR gene activation of human microtubule associated protein 1 light chain 3 gamma

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MAP1LC3C
• Locus ID: 440738
• Components:

  GA118477G1, LC3C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118477G2, LC3C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118477G3, LC3C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001004343
• UniProt ID: Q9BXW4
• Synonyms: ATG8J; LC3C
• Summary: Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).[supplied by OMIM, Nov 2010]