Human PRSS57 activation kit by CRISPRa

SKU GA118277

PRSS57 CRISPRa kit - CRISPR gene activation of human serine protease 57

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PRSS57
• Locus ID: 400668
• Components:

  GA118277G1, PRSS57 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118277G2, PRSS57 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118277G3, PRSS57 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001308209, NM_214710
• UniProt ID: Q6UWY2
• Synonyms: NSP4; PRSSL1; UNQ782
• Summary: This gene encodes an arginine-specific serine protease and member of the peptidase S1 family of proteins. The encoded protein may undergo proteolytic activation before storage in azurophil granules, in neutrophil cells of the immune system. Following neutrophil activation, the protease is released into the pericellular environment, where it may play a role in defense against microbial pathogens. [provided by RefSeq, Jul 2016]