Human MFSD2B activation kit by CRISPRa

SKU GA118007

MFSD2B CRISPRa kit - CRISPR gene activation of human major facilitator superfamily domain containing 2B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MFSD2B
• Locus ID: 388931
• Components:

  GA118007G1, MFSD2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA118007G2, MFSD2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA118007G3, MFSD2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001080473, NM_001346880
• UniProt ID: A6NFX1
• Summary: Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets (PubMed:29045386). Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology (By similarity). Does not transport lysophosphatidylcholine (LPC) (By similarity).[UniProtKB/Swiss-Prot Function]