Human LCE3A activation kit by CRISPRa

SKU
GA117716
LCE3A CRISPRa kit - CRISPR gene activation of human late cornified envelope 3A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LCE3A
Locus ID 353142
Components

GA117716G1, LCE3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117716G2, LCE3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117716G3, LCE3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_178431
UniProt ID Q5TA76
Synonyms LEP13
Summary A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035).UniProtKB/Swiss-Prot Function
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Other Versions
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KN222176 LCE3A - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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