Human MACC1 activation kit by CRISPRa

SKU
GA117625
MACC1 CRISPRa kit - CRISPR gene activation of human MET transcriptional regulator MACC1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MACC1
Locus ID 346389
Components

GA117625G1, MACC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117625G2, MACC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117625G3, MACC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_182762
UniProt ID Q6ZN28
Synonyms 7A5; SH3BP4L
Summary MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 PubMed 19098908).supplied by OMIM, Mar 2009
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Other Versions
SKU Description Size Price
KN424774 MACC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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