Human NANOS1 activation kit by CRISPRa

SKU GA117499

NANOS1 CRISPRa kit - CRISPR gene activation of human nanos C2HC-type zinc finger 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NANOS1
• Locus ID: 340719
• Components:

  GA117499G1, NANOS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117499G2, NANOS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117499G3, NANOS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001009553, NM_199461
• UniProt ID: Q8WY41
• Synonyms: nanos homolog 1; nanos homolog 1 (Drosophila); NOS1; OTTHUMP00000046853
• Summary: This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in this gene are associated with spermatogenic impairment. [provided by RefSeq, Sep 2015]