Human ABCB5 activation kit by CRISPRa

SKU GA117469

ABCB5 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily B member 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ABCB5
• Locus ID: 340273
• Components:

  GA117469G1, ABCB5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117469G2, ABCB5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117469G3, ABCB5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001163941, NM_001163942, NM_001163993, NM_178559
• UniProt ID: Q2M3G0
• Synonyms: ABCB5alpha; ABCB5beta; EST422562
• Summary: ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]