Human CCDC66 activation kit by CRISPRa

SKU GA117212

CCDC66 CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 66

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CCDC66
• Locus ID: 285331
• Components:

  GA117212G1, CCDC66 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117212G2, CCDC66 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117212G3, CCDC66 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001012506, NM_001130911, NM_001141947, NR_024460, NM_001353147, NM_001353148, NM_001353149, NM_001353150, NM_001353151, NM_001353152, NM_001353153, NM_001353154, NM_001353155, NM_001353156, NM_001353158, NM_001353160, NR_148366, NR_148367, NR_148368, NR_148369, NR_148370, NR_148371, NR_148372, NR_148373, NR_148374, NR_148375, NR_148376, NR_148377, NR_148378
• UniProt ID: A2RUB6
• Synonyms: DKFZp686C0433
• Summary: Microtubule-binding protein required for ciliogenesis (PubMed:28235840). May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites (PubMed:28235840). Plays a role in retina morphogenesis and/or homeostasis (By similarity).[UniProtKB/Swiss-Prot Function]