Human RSPO1 activation kit by CRISPRa

SKU
GA117171
RSPO1 CRISPRa kit - CRISPR gene activation of human R-spondin 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RSPO1
Locus ID 284654
Components

GA117171G1, RSPO1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117171G2, RSPO1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117171G3, RSPO1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001038633, NM_001242908, NM_001242909, NM_001242910, NM_173640
UniProt ID Q2MKA7
Synonyms CRISTIN3; RSPO
Summary This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN417921 RSPO1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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