Human PGP activation kit by CRISPRa

SKU
GA117067
PGP CRISPRa kit - CRISPR gene activation of human phosphoglycolate phosphatase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PGP
Locus ID 283871
Components

GA117067G1, PGP gRNA vector 1 in pCas-Guide-GFP-CRISPRa, Target Sequence: GAGCGCTTCACTCCGAATGC

GA117067G2, PGP gRNA vector 2 in pCas-Guide-GFP-CRISPRa, Target Sequence: TGGCGAAGGTGCAGGCCAAT

GA117067G3, PGP gRNA vector 3 in pCas-Guide-GFP-CRISPRa, Target Sequence: TTGGCTGGCAGGGCTCCAAC

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001042371
UniProt ID A6NDG6
Synonyms AUM; G3PP; PGPase
Summary Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:26755581). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN414470 PGP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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