Human CES4A activation kit by CRISPRa

SKU
GA117063
CES4A CRISPRa kit - CRISPR gene activation of human carboxylesterase 4A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CES4A
Locus ID 283848
Components

GA117063G1, CES4A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117063G2, CES4A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117063G3, CES4A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001190200, NM_001190201, NM_001190202, NM_001318506, NM_173815, NM_001364782
UniProt ID Q5XG92
Synonyms CES6; FLJ37002; FLJ37464
Summary This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined. provided by RefSeq, Jun 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN416384 CES4A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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